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It is known that the harmful effects of ROS are controlled by various cellular defense systems consisting of enzymatic components (catalase, glutathione peroxidase and superoxide dismutase, etc.)

Bo Wang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, due to the narrow therapeutic window, severe adverse effects, and rapid disease progression, the therapeutic efficacy of NAC is still limited ( Recently, herbal medicine was found to be a promising therapeutic approach for ALI

The optimum pH was determined by performing enzymatic assays at different pH levels (4.7 to 9.76) at 37C